Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern

نویسندگان

  • Kerry H. Lok
  • William H. Benjamin
  • Michael E. Kimerling
  • Virginia Pruitt
  • Donna Mulcahy
  • Nancy Robinson
  • Nancy B. Keenan
  • Nancy E. Dunlap
چکیده

We conducted a program of population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2452 isolates, 1013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2002